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The pathogenesis of immune thrombocytopaenic purpura
Author(s) -
Cooper Nichola,
Bussel James
Publication year - 2006
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.2006.06024.x
Subject(s) - medicine , purpura (gastropod) , disease , pathogenesis , immunology , immune system , autoimmune disease , immune thrombocytopenia , platelet , biology , ecology
Summary Immune thrombocytopaenic purpura (ITP) is an autoimmune bleeding disease that is rarely fatal. However, in many adults treatment is unsatisfactory, with as much morbidity from the immunosuppressive effects of treatment as from bleeding. Identifying the underlying disease process should help us to identify more targeted therapies and improve not only the treatment but also the quality of life of patients with this disorder.