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Soluble c‐kit levels in acute GVHD after allogeneic bone marrow transplantation
Author(s) -
Hashino Santoshi,
Imamura Masahiro,
Kobayashi Sumiko,
Tanaka Junji,
Kasai Masaharu,
Sakurada Keisuke,
Asaka Masahiro
Publication year - 1995
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1995.tb08431.x
Subject(s) - medicine , bone marrow transplantation , transplantation , bone marrow , hematology , immunology
Serum soluble c‐kit concentrations were measured in 11 patients with or without acute graft‐versus‐host disease (GVHD) after allogeneic bone marrow transplantation. The serum soluble c‐kit levels in the patients with moderate to severe acute GVHD (grade II‐IV) were significantly lower than those in the patients with no or mild acute GVHD (grade 0‐I) following the onset. The data from this study indicate that measurement of serum soluble c‐kit concentration is a useful indicator of severe acute GVHD.