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Incidence of human parvovirus B19 DNA detection in blood donors
Author(s) -
Yoto Yuko,
Kudoh Tooru,
Haseyama Keiji,
Suzuki Nobuhiro,
Oda Takanori,
Katoh Toshiaki,
Takahashi Tsuneo,
Sekiguchi Sadami,
Chiba Shunzo
Publication year - 1995
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1995.tb05427.x
Subject(s) - parvovirus , incidence (geometry) , parvoviridae , nested polymerase chain reaction , virology , immunology , dna , blood transfusion , medicine , polymerase chain reaction , hematology , biology , virus , gene , genetics , physics , optics
Summary. 1000 serum samples from blood donors were tested for human parvovirus B19 (B19) DNA by a nested PCR assay: six samples were positive for B19 DNA. The frequency was 1/167 (0‐6%), considerably higher than previous surveys (0‐004‐0‐03%). Five of the six samples were also positive for anti‐B19 IgM, indicating an acute phase of infection. It is recommended to screen for B19 DNA in blood products to prevent transfusion mediated viral infection for those susceptible such as immunocompromised patients and pregnant women.