Premium
Splenectomy for treatment of immunoblastic lymphadenopathy
Author(s) -
Hirose Masao,
Nakagawa Ryuji,
Okada Akira,
Sano Toshiaki,
Kuroda Yasuhiro
Publication year - 1994
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1994.tb08337.x
Subject(s) - splenectomy , medicine , immunology , spleen
Summary. A 5‐month‐old girl was diagnosed with immunoblastic lymphadenopathy (IBL) on the basis of clinical symptoms and pathological findings. α‐interferon. immunosuppressive agents such as cyclosporin A, deoxyspagarine, and azathioprine, and an alternating regimen of low‐dose 6‐ mercaptopurine, cyclophosphamide and methotrexate were tried with partial success. Finally, splenectomy was carried out at 58 months of age, inducing prolonged complete remission without any medication.