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Scedosporium inflatum infection in immunocompromised haematological patients
Author(s) -
Tapia Manuel,
Richard Carlos,
Baro Julio,
Salesa Ricardo,
Figols Javier,
Zurbano Felipe,
Zubizarreta Alberto
Publication year - 1994
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1994.tb04897.x
Subject(s) - scedosporium apiospermum , pathological , medicine , antifungal , hematology , pathology , intensive care medicine , dermatology , voriconazole
Summary We report four cases of Scedosporium inflatum (S. inflatum) infection in severely immunocompromised haematological patients. Six well‐documented cases of S. inflatum disseminated infection in haematological patients have been reported: four in Australia and two in Spain. Their clinical and pathological characteristics are heterogenous, particularly in the Australian cases. However, the clinical and pathological profile emerging from our and other Spanish cases is homogenous and very similar to the clinico‐pathological spectrum of other disseminated mycoses, including Aspergillus and S. apiospermum . The optimal treatment of S. inflatum infection is unknown and the outcome in haematological patients is very poor. Eight patients died despite systemic antifungal treatment.