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Sweet's syndrome during therapy with granulocyte colony‐stimulating factor in a patient with aplastic anaemia
Author(s) -
Fukutoku Masaaki,
Shimizu Shiro,
Ogawa Yoshimi,
Takeshita Shouichi,
Masaki Yasuhumi,
Arai Toshihide,
Hirose Yuko,
Sugai Susumu,
Konda Susumu,
Takiguchi Tomoo
Publication year - 1994
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1994.tb04799.x
Subject(s) - medicine , sweet's syndrome , granulocyte colony stimulating factor , aplastic anemia , granulocyte , sweet syndrome , gastroenterology , surgery , immunology , chemotherapy , dermatology , bone marrow
Summary. A patient with aplastic anaemia developed Sweet's syndrome (a febrile neutrophilic dermatosis) during granulocyte colony‐stimulating factor (G‐CSF) therapy. Three repeated episodes of appearance and disappearance of erythematous nodules after administration and withdrawal of G‐CSF confirmed that G‐CSF induced Sweet's syndrome in the patient. Sweet's syndrome has been reported in patients with myelodysplastic syndrome and acute leukaemia, but not in patients with aplastic anaemia. This is the first report of a patient with aplastic anaemia who developed G‐CSF‐induced Sweet's syndrome.