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Platelet aggregation in response to four low molecular weight heparins and the heparinoid ORG 10172 in patients with heparin‐induced thrombocytopenia
Author(s) -
Keeling D. M.,
Richards E. M.,
Baglin T. P.
Publication year - 1994
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1994.tb04760.x
Subject(s) - heparinoid , heparin , platelet , platelet aggregation , chemistry , low molecular weight heparin , pharmacology , medicine
Summary A simple rapid platelet aggregation test was used to evaluate cross‐reactivity of four low molecular weight heparins and the heparinoid ORG 10172 in three patients with heparin‐induced thrombocytopenia. The low molecular weight heparins cross‐reacted in 11 out of 12 tests. The heparinoid ORG 10172 did not cross‐react in any of the patients. One patient was treated with ORG 10172 and thrombocytopenia resolved.