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Control of polycythaemia vera with photochemotherapy in a patient with cutaneous T‐cell lymphoma
Author(s) -
Cottrill Carolyn,
Geller Alex,
DiSpaltro Francis X.,
Weissglass Bennett,
Klainer Albert S.,
Bisaccia Emil
Publication year - 1994
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1994.tb03286.x
Subject(s) - phlebotomy , medicine , polycythaemia , polycythemia vera , cutaneous t cell lymphoma , dermatology , lymphoma , malignancy , mycosis fungoides , immunology
We report the use of photochemotherapy in a patient with polycythaemia vera (PV) and cutaneous T‐cell lymphoma (CTCL). The patient was diagnosed with PV and required monthly phlebotomy. Subsequently he was diagnosed with CTCL and was started on photochemotherapy. A clinical improvement in both conditions, with haematocrit stabilizing at a level of 50%, eliminated the need for further phlebotomy. It is conceiveable that photochemotherapy induced the clinical and laboratory improvement in PV by targeting the aberrant clonal haemopoietic cell, similar to the mechanism thought to be operative in CTCL, a clonal helper T cell malignancy.