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Aberrant CD8 antigen expression in a patient with B chronic lyrnphocytic leukaemia showing unusual disease progression
Author(s) -
Ghosh K.,
Sivakumaran M.,
Wood J. K.
Publication year - 1993
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1993.tb08673.x
Subject(s) - cd5 , antigen , immunology , cd8 , disease , medicine , pathology
Summary. Co‐expression of T cell antigens in B‐CLL has been well recognized. The commonest T cell antigen known to be expressed in B‐CLL is CD 5, and recent reports suggest that CU 5 expression is associated with good prognosis. Expression of CD8 antigen, however, is much less common with uncertain prognostic significance. We report a case of B‐CLL with aberrant CD8 expression, who had unusual disease progression with a fatal outcome.