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Sweet's syndrome associated with G‐CSF
Author(s) -
Paydas Semra,
Sahin Berksoy,
Seyrek Ertugrul,
Soylu Merih,
Gonlusen Gulfiliz,
Acar Alparslan,
Tuncer Ilhan
Publication year - 1993
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1993.tb08668.x
Subject(s) - medicine , sweet's syndrome , immunology
Summary. Sweet's syndrome (SS) developed in two patients with acute myeloid leukaemia (AML) treated with granulocyte colony stimulating factor (G‐CSF) for febrile neutropenia due to AML chemotherapy. Fever, painful skin and conjunctival lesions developed and neutrophilic infiltration was detected at biopsy specimens. Neutrophilia was not detected. Skin lesions regressed within 1–2 weeks and conjunctival lesions within 4 weeks following the cessation of G‐CSF. We conclude that SS may be a complication of G‐CSF therapy and tender skin and/or conjunctival lesions developing during G‐CSF therapy should suggest the possibility of SS.