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Unreliability in immunoassays of erythropoietin: anomalous estimates with an assay kit
Author(s) -
Bechensteen A. G.,
Lappin T. R. J.,
Marsden J.,
Muggleston D.,
Cotes P. M.
Publication year - 1993
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1993.tb04708.x
Subject(s) - erythropoietin , immunoassay , medicine , immunology , antibody
Summary. We report the finding of inappropriately high estimates of erythropoietin (Epo) in 11% of serum samples tested by one commercial assay kit. These estimates were not confirmed when the same samples were tested independently in four other systems for the immunoassay of Epo. As yet no explanation has been found to account for the anomalously high estimates.