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Heparin‐induced skin reaction due to two different preparations of low molecular weight heparin (LMWH)
Author(s) -
Phillips J. K.,
Majumdar G.,
Hunt B. J.,
Savidge G. F.
Publication year - 1993
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1993.tb03080.x
Subject(s) - heparin , medicine , low molecular weight heparin , complication , anticoagulant , skin reaction , surgery , anesthesia , pharmacology , dermatology
Summary. Heparin‐induced skin reaction is a recognized complication of subcutaneously administered, unfractionated heparin, and has recently been described in association with the use of two LMWH preparations. Fragmin and Fraxiparin. We describe the case of a 25‐year‐old woman in whom characteristic skin lesions were induced on separate occasions by unfractionated heparin, Fragmin and a third preparation of LMWH, Clexane. This case demonstates that substitution of one preparation of heparin for another does not prevent recurrence of skin reaction in susceptible patients. Alternative anticoagulants should be considered in these cases.