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Pulmonary fibrosis with megakaryocytoid cell infiltration in accelerated phase of chronic myelogenous leukaemia
Author(s) -
Yamauchi Kunihiko,
Oda Koji,
Shimamura Kazuo,
Arimori Shigeru,
Nagao Tadami
Publication year - 1993
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1993.tb03073.x
Subject(s) - medicine , chronic myelogenous leukemia , infiltration (hvac) , pulmonary fibrosis , fibrosis , pathology , leukemia , physics , thermodynamics
Summary. We report a patient in the accelerated phase of Philadelphia‐chromosome‐positive chronic myelogenous leukaemia who developed fibrosis in lungs, spleen and bone marrow. In the lungs, fibrosis was demonstrated in the alveolar septa which had been infiltrated by giant, bizarreshaped cells resembling the megakaryocytes in the bone marrow. The relationship between the fibrosis and megakaryocytoid cell infiltration in the lungs is discussed.