Premium
A new method to study the efficiency of third generation blood filters
Author(s) -
Sivakumaran M.,
Norfolk D. R.,
Major K. E.,
Revill J. A.,
Hutchinson R. M.,
Wood J. K.
Publication year - 1993
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1993.tb03045.x
Subject(s) - filtration (mathematics) , filter (signal processing) , biomedical engineering , polycarbonate , membrane , priming (agriculture) , materials science , chemistry , medicine , mathematics , computer science , biology , statistics , composite material , biochemistry , germination , botany , computer vision
Summary. In order to study the efficiency of third generation blood filters we have devised a new method using 3 μm pore size polycarbonate filter membranes and a filtration chamber to trap leucocytes passing through the blood filter. The method has enabled us to make two important observations: (1) The filters function very efficiently at the start but the efficiency diminishes progressively with time. (2) When the blood flow through the filter is retarded, due to defective priming and/or filter malfunction, the filters fail even at the outset of the transfusion.