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Successful childbirth by a patient with congenital factor XI deficiency and an acquired inhibitor
Author(s) -
Ginsberg Steven S.,
Clyne Lionel P.,
McPhedran Peter,
Duffy Thomas P.,
Hanson† T.
Publication year - 1993
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1993.tb03044.x
Subject(s) - childbirth , medicine , pediatrics , pregnancy , genetics , biology
Summary. Acquired inhibitors in factor XI deficiency (FXI) are rare. The presence of an inhibitor during pregnancy poses a potential haemorrhagic risk to the fetus. We report an uncomplicated pregnancy and successful childbirth by a woman with congenital FXI deficiency and an acquired inhibitor, and discuss the persistence of residual FXI activity in the presence of an inhibitor.