Premium
An improved acidified glycerol lysis test (AGLT) used to detect spherocytes in pregnancy
Author(s) -
Acharya J.,
Ferguson I. L. C.,
Cassidy A. G.,
Grimes. A. J.
Publication year - 1987
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1987.tb06865.x
Subject(s) - glycerol , lysis , pregnancy , pregnancy test , andrology , zoology , medicine , immunology , biology , toxicology , biochemistry , genetics
Summary. The acidified glycerol lysis test (Zanella et al, 1980) had proved unreliable in our hands. We now report the test to be stable and reliable when conducted at 37°C rather than at ambient laboratory temperature as used by earlier workers. With this modification, blood samples were tested from 167 pregnant subjects. Forty‐eight were less than 26 weeks pregnant and gave normal AGLT values (T 50 > 1800 s) while of 119 more than 26 weeks pregnant 57 (48%) gave shortened T 50 values indicative of the presence of spherocytes.