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An acute leukaemia augured before clinical signs by blood group antigen abnormalities and low levels of A and H blood group transferase activities in erythrocytes
Author(s) -
Lopez M.,
BonnetGajdos M.,
Reviron M.,
Janvier D.,
Huet M.,
Salmon Ch.
Publication year - 1986
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1986.tb07531.x
Subject(s) - medicine , malignancy , leukemia , gastroenterology , agglutination (biology) , immunology , antigen
S ummary A mixed field agglutination pattern with anti‐A reagents and very low levels of A and H blood group antigen specific transferase activities were found in the erythrocytes of a 4‐year‐old girl who presented no clinical signs of haematological disease. Blood and marrow examination displayed some features consistent with a moderate dysmyelopoietic state. 18 months later an acute myeloblastic leukaemia confirmed the suspected haematological malignancy.