Premium
A study of lymphocyte subsets in patients with angioimmunoblastic lymphadenopathy
Author(s) -
Pálóczi K.,
Surányi P.,
Nemes Z.,
Szegedi Gy.
Publication year - 1986
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1986.tb04083.x
Subject(s) - medicine , lymphocyte , immunology , lymphocyte subsets , pathology , t cell , immune system
Summary Immunological marker studies of peripheral blood lymphocytes in 22 patients with typical angioimmunoblastic lymphadenopathy were carried out. There was a decrease of the absolute lymphocyte number, of T‐helper cells and the T4/T8 ratio in the active stage of the disease. The active T‐cells and total Tcells were reduced both in the active and in the inactive state. The number of B‐cells was in both states increased. Implications and possible mechanism of these observations are discussed.