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T‐cell origin of Lennert's lymphoma
Author(s) -
O'Connor N. T. J.,
Feller A. C.,
Wainscoat J. S.,
Gatter K. C.,
Pallesen G.,
Stein H.,
Lennert K.,
Mason D. Y.
Publication year - 1986
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1986.tb02208.x
Subject(s) - lymphoma , gene , gene rearrangement , germline , immunoglobulin light chain , antibody , biology , genetics , immunology
S ummary . The arrangement of the T‐cell receptor and immunoglobulin genes has been analysed in five cases of Lennert's lymphoma. All cases showed rearrangement of the gene coding for the β chain of the T‐cell receptor and a germline configuration of the immunoglobulin genes. This provides strong evidence that Lennert's lymphoma is a T‐cell lymphoma.