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Multiple myeloma in a pair of monozygotic twins: the first reported case
Author(s) -
Judson I. R.,
Wiltshaw E.,
Newland A. C.
Publication year - 1985
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1985.tb07452.x
Subject(s) - multiple myeloma , etiology , identical twins , brother , medicine , monozygotic twin , disease , pediatrics , pathology , immunology , genetics , biology , political science , law
S ummary A pair of monozygotic twins both developed multiple myeloma within a 2 year period. The first patient is alive with stable disease 4 years later, his twin brother died within a year of diagnosis. Monozygosity is well established and in both cases the paraprotein was IgG K . The relative influence of environmental and hereditary factors on the aetiology of myeloma is discussed. We believe this to be the first case of myeloma in twins to be reported.