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A study of the effects of treating platelets with paraformaldehyde for use in the platelet suspension immunofluorescence test
Author(s) -
Magee J. M.
Publication year - 1985
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1985.tb02855.x
Subject(s) - paraformaldehyde , platelet , immunofluorescence , medicine , antibody , suspension (topology) , red cell , immunology , pathology , mathematics , homotopy , pure mathematics
S ummary . Discrepant results when paraformaldehyde (PFA) treated and untreated platelets were used in parallel in the platelet suspension immunofluorescence test (PSIFT) (von dem Borne et al , 1978) prompted further investigation of the sera of a group of patients suffering from chronic renal failure (CRF). The demonstration of a positive result in the PSIFT when only PFA treated platelets were used appears to be linked to the N like red cell antibody described in some patients suffering from CRF.