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Chloroquine stripping of HLA antigens from neutrophils without removal of neutrophil specific antigens
Author(s) -
Minchinton R. M.,
Waters A. H.
Publication year - 1984
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1984.tb02948.x
Subject(s) - antigen , immunology , human leukocyte antigen , antibody , chloroquine , medicine , malaria
S ummary. Chloroquine stripping removes HLA antigens from neutrophils without damage to neutrophil specific antigens. This offers, for the first time, a simple procedure for the demonstration of neutrophil specific antibodies in sera that also contain HLA antibodies.