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Serum transcobalamin levels as an early indicator of bone marrow engraftment following transplantation
Author(s) -
Naparstek E.,
Rachmilewitz B.,
Rachmilewitz M.,
Fuks Z.,
Slavin S.
Publication year - 1983
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1983.tb01242.x
Subject(s) - bone marrow transplantation , bone marrow , peripheral blood , medicine , transplantation , white blood cell , immunology , pathology
S ummary . Three B 12 binding proteins, the transcobalamins TCI, TCII and TCIII, were determined serially in the serum of five patients who underwent bone marrow transplantation. The increase in TCII, followed by the increase in TCI, proved to be an early indicator of bone marrow regeneration, reaching a peak of up to twice its normal levels at least 5 d prior to the rise of the peripheral white blood cell count.