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Globin gene mapping in normal Hb A 2 types of β‐thalassaemia
Author(s) -
Kanavakis E.,
MetaxotouMavromati A.,
Kattamis C.,
Aksoy M.,
Weatherall D. J.,
Wood W. G.
Publication year - 1982
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1982.tb07289.x
Subject(s) - gene , globin , genetics , hemoglobinopathy , biology , thalassemia , microbiology and biotechnology , hemolytic anemia , immunology
Globin‐gene mapping of DNA from 13 families with normal Hb A 2 β‐thalassaemia (both type 1 and type 2) failed to detect any difference from normal in their globin‐gene arrangement. We conclude that deletions such as those responsible for γβ‐thalassaemia or a ‘silent’ Hb Lepore are not responsible for this type of β‐thalassaemia in Greece.