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α‐Globin gene deletions associated with Hb J Tongariki
Author(s) -
Bowden D. K.,
Pressley L.,
Higgs D. R.,
Clegg J. B.,
Weatherall D. J.
Publication year - 1982
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1982.tb02777.x
Subject(s) - genetics , haplotype , gene , globin , mutation , thalassemia , hemoglobinopathy , biology , alpha globulin , alpha thalassemia , microbiology and biotechnology , allele , hemolytic anemia , genotype , immunology
S ummary . Three different α + thalassaemia genes, one of which always carries the Hb J Tongariki mutation, have been observed in Vanuatuans. Despite the fact that at least two of them have arisen by different types of crossover event, the expression of all three haplotypes is identical.