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Waldenström‐like Lymphoma with Monoclonal IgG 1 kappa: Evidence of Common Clonal Origin
Author(s) -
Waele Marc De,
Coulie Roland,
Camp Benjamin Van
Publication year - 1981
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1981.00095.x
Subject(s) - lymphocytosis , monoclonal , bone marrow , lymphoplasmacytic lymphoma , lymphoma , pathology , monoclonal antibody , medicine , population , immunology , lymphoproliferative disorders , waldenstrom macroglobulinemia , antibody , environmental health
S ummary. A patient with a pleomorphic lymphoplasmacytic bone marrow infiltration, a peripheral lymphocytosis and a monoclonal IgG 1 ‐κ gammopathy is described. An antiidiotype serum, raised against the monoclonal serum protein showed a common clonal origin of the pleomorphic cell population. In the light of recent reports on B‐cell neoplasms associated with M‐components, a hypothetical scheme of the cellular clonal event is proposed.