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Non‐spherocytic Haemolytic Anaemia in Mother and Son Associated with Hexokinase Deficiency
Author(s) -
Newman P.,
Muir A.,
Parker A. C.
Publication year - 1980
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1980.tb06010.x
Subject(s) - hexokinase , medicine , glucose 6 phosphate dehydrogenase deficiency , immunology , glycolysis , metabolism
S ummary . The case history, laboratory findings and properties of the enzyme in a patient with hexokinase deficiency are reported. The mother had a haemolytic disorder of similar severity. In these cases the expression of the disease in both mother and son suggests a dominant mode of inheritance. This family further illustrates the necessity of taking the reticulocyte level into account when interpreting red cell enzyme levels.