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Urinary β‐Thromboglobulin in Essential Hypertension
Author(s) -
Anderton J. L.,
Fananapazir L.,
Dawes Joan
Publication year - 1980
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1980.tb01213.x
Subject(s) - urinary system , medicine , renal function , essential hypertension , endocrinology , platelet , population , gastroenterology , blood pressure , environmental health
S ummary . Urinary concentrations of the platelet‐specific protein β‐thromboglobulin (β‐TG) were measured in patients with essential hypertension. Values obtained for patients with normal renal function fell within the same population as those for a control group of normal individuals, but nevertheless 21% of these patients had urinary β‐TG values above the upper limit of the normal range. Values for patients with renal insufficiency were significantly different from the other groups, and 44% of these individuals had abnormally elevated urinary β‐TG concentrations. These elevated values may reflect an increased plasma concentration of β‐TG in patients with renal impairment or they could be an indicator of renal damage.