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The Incidence of Antibodies to Low Frequency Antigens (LFA) in Plasmapheresis Donors with Hyperimmune Rh Antisera
Author(s) -
Contreras M.,
Barbolla L.,
Lubenko A.,
Armitage S. E.
Publication year - 1979
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1979.tb05875.x
Subject(s) - plasmapheresis , antiserum , antibody , medicine , incidence (geometry) , virology , antigen , immunology , isoantibodies , physics , optics
S ummary . Over 50% of plasmas from plasmapheresis donors hyperimmunized for Rh antibodies were found to contain antibodies to low frequency red cell antigens (LFA). The majority of these plasmas contained antibodies to more than one LFA. On the other hand, the incidence of these antibodies in immune plasma from control plasmapheresis donors was markedly lower. The significance of the high incidence of these antibodies in grouping reagents is discussed.