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37°C E Rosettes in Various Malignant and Non‐malignant Disorders
Author(s) -
Palutke Margarita,
Tabaczka Pamela,
Varadachari Chandra,
Carrillo Gilda
Publication year - 1979
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1979.tb03763.x
Subject(s) - lymph , malignant lymphoma , pathology , lymphoma , medicine , lymphocyte , malignant cells , malignant disease , t cell , lymph node , t lymphocyte , immunology , immune system , biology , cancer
S ummary . T lymphocytes, forming sheep erythrocyte rosettes at 37°C, have been described in thymus glands, mitogen and allogeneic cell stimulated lymphocyte cultures, and acute T cell lymphoblastic leukaemia. This paper describes the finding of such lymphocytes in lymph nodes of a variety of disorders including Hodgkin's disease, Lennert's lymphoma, malignant lymphoma of large transformed T lymphocytes, immunoblastic lymphadenopathy, metastatic carcinoma, and other disorders. A large number of tonsils, but not reactive lymph nodes, also contained a significant number of those T lymphocytes. The significance of these findings in relation to interpretation of immune red cell rosettes and to the subclasses of T lymphocytes is discussed.