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The Reticulin Content of Bone Marrow in Acute Leukaemia in Adults
Author(s) -
Manoharan A.,
Horsley R.,
Pitney W. R.
Publication year - 1979
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1979.tb03740.x
Subject(s) - bone marrow , medicine , pathology , biopsy , trephine , bone marrow examination
S ummary . Marrow reticulin was studied by trephine biopsy in 44 patients with adult acute leukaemia at presentation and subsequently during the course of their illness. The findings indicate that: (1) an increase in marrow reticulin is common at presentation in patients with both acute lymphoblastic and acute non‐lymphoblastic leukaemia; (2) effective anti‐leukaemic therapy results in resolution of some or all of the increased marrow reticulin and is not contraindicated, even in patients with a marked increase in marrow reticulin; and (3) reappearance of an increase in marrow reticulin may be a sign of relapse of the leukaemia.