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Identification of the Hairy Cells of Leukaemic Reticuloendotheliosis by an Esterase Method
Author(s) -
Higgy K. E.,
Burns G. F.,
Hayhoe F. G. J.
Publication year - 1978
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1978.tb07112.x
Subject(s) - esterase , pathology , medicine , biology , immunology , enzyme , biochemistry
S ummary A distinctive pattern of alpha‐naphthyl butyrate esterase positivity was observed in all of a series of 14 patients with HCL. This pattern was not observed in a range of other haematological malignancies including nine cases of CLL, two cases of Sézary's syndrome, six cases of null cell ALL, two cases of Schilling‐type monocytic leukaemia and one case of lymphosarcoma cell leukaemia. The potential diagnostic value of this simple cytochemical test is discussed in relation to existing methods.