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Platelet and Plasma β Thromboglobulin in Mycloproliferative Syndromes and Secondary Thrombocytosis
Author(s) -
Boughton U. J.,
Aliington M. J.,
King A.
Publication year - 1978
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1978.tb03646.x
Subject(s) - thrombocytosis , platelet , medicine , aspirin , thrombosis , gastroenterology , beta thromboglobulin , platelet factor 4 , immunology
SUMMARY Elevated plasma β thromboglobulin (βtg) and decreased intracellular platelet βtg were found in patients with various myeloproliferative disorders. In secondary thrombocytosis, similar, but less marked changes were found. The abnormalities were increased during episodes of clinical thrombosis and could be suppressed in two‐thirds of cases by aspirin therapy.