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Auto Analyzer Determination of Red Cell Kell Phenotypes in Patients with Chronic Granulomatous Disease (CGD) and Heterozygous Carriers
Author(s) -
Bowell P.J.,
Hill F. G. H.
Publication year - 1978
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1978.tb01107.x
Subject(s) - autoanalyzer , chronic granulomatous disease , phenotype , red cell , medicine , immunology , antigen , pathology , disease , biology , genetics , gene
One of six boys with chronic granulomatous disease was shown to have the rare Kell phenotype, McLeod, by both manual and AutoAnalyzer techniques. Using the AutoAnalyzer, the red cells of this boy's mother were clearly shown to have weaker expression of k and Kp b antigens than those of the controls, whereas the Kell groups on the father's red cells appeared normal.