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Intravascular Phagocytosis in the Rabbit Bone Marrow: A Possible Fate of Normal Senescent Red Cells
Author(s) -
Tavassoli Mehdi
Publication year - 1977
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1977.tb00655.x
Subject(s) - phagocytosis , bone marrow , cytoplasm , pathology , microbiology and biotechnology , penetration (warfare) , rabbit (cipher) , biology , chemistry , immunology , medicine , statistics , mathematics , operations research , engineering
Perisinal macrophages in the rabbit bone marrow can penetrate the sinus wall and phagocytose circulating red cells intraluminally. Serial sectioning reveals that the penetration occurs through the cytoplasm of a single endothelial cell. This phenomenon may provide an effective mechanism for monitoring the circulation and removing normal senescent red cells.