Premium
Lymphoid Cell Dependent (K‐Cell) Lysis of Human Erythrocytes Sensitized with Rhesus Alloantibodies
Author(s) -
Urbaniak S. J.
Publication year - 1976
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1976.tb03558.x
Subject(s) - lysis , immunology , isoantibodies , antibody , in vitro , red blood cell , homologous chromosome , cell , peripheral blood , microbiology and biotechnology , biology , chemistry , medicine , biochemistry , gene
S ummary . An in vitro homologous system using human Rhesus alloantibodies and target erythrocytes labelled with 51 Cr has been used to demonstrate the ability of normal peripheral blood lymphoid cells to lyse antibody‐coated human red cells. The results obtained suggest that this type of mechanism may be relevant to certain haemolytic diseases in man.