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The Use of a Single Venous Blood Sample to Assess Oxygen Binding to Haemoglobin
Author(s) -
Lichtman Marshall A.,
Murphy Marion,
Pogal Meredith
Publication year - 1976
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1976.tb01878.x
Subject(s) - polycythaemia , venous blood , oxygen delivery , oxygen , medicine , red cell , chemistry , organic chemistry
S ummary . The measurement of pH, Po 2 , Pco 2 and So 2 in a single venous blood sample can be used to determine the P 50 at standard or at in vivo conditions. This technique makes it feasible for a physician, firstly, to make an assessment of the net adaptation of the red cell to reductions in blood oxygen content or flow and, secondly, to make an initial assessment of whether a haemoglobin with altered affinity for oxygen is present in subjects with polycythaemia or anaemia.