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Lysosomal Acid Hydrolases in Human Lymphocyte Subpopulations
Author(s) -
Barr R. D.,
Perry S.
Publication year - 1976
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1976.tb00960.x
Subject(s) - acid phosphatase , beta glucuronidase , glucuronidase , staining , biology , null cell , granule (geology) , microbiology and biotechnology , lymphocyte , cytochemistry , immunology , enzyme , biochemistry , genetics , gene expression , paleontology , gene
Acid phosphatase and beta‐glucuronidase activities have been determined cytochemically in T, B and null lymphocytes as part of an effort to characterize the human haemopoietic stem cell. A combination of weak acid phosphatase activity and strong beta glucuronidase staining, in the form of a single large granule, has been shown to be specific for T cells. On the basis of this approach alone, non‐T cells could not be further subclassified. Further cytochemical evaluation is being explored.