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The Use of an Image Analysing Computer for the Quantitation of Red Cell Morphological Characteristics
Author(s) -
Bentley S. A.,
Lewis S. M.
Publication year - 1975
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1975.tb01801.x
Subject(s) - red cell , computer science , computational biology , artificial intelligence , pathology , medicine , biology
S ummary . Measurements of integrated optical density and projected area of red cells have been made on Romanowsky‐stained blood films from 25 subjects using an image analysing computer. Close correlation was observed between mean cell projected area and MCV and between mean cell integrated optical density and MCH. Mean values for the quotient of cell integrated density/cell projected area (mean cell colour density) correlated with MCHC. Variances of cell area and colour density correlated subjectively with anisocytosis and anisochromasia, and histograms of these parameters demonstrated dual populations. The clinical application of these findings is discussed.