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Acute Leukaemia with Eosinophilia or Acute Eosinophilic Leukaemia: A Dilemma
Author(s) -
Weinger R. S.,
AndréSchwartz Janine,
Desforges Jane F.,
Baker Margaret
Publication year - 1975
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1975.tb00518.x
Subject(s) - eosinophilic , eosinophil , eosinophilia , bone marrow , medicine , pathology , peripheral blood , immunology , asthma
S ummary . A young male patient is described with acute leukaemia whose bone marrow and peripheral blood contained abundant cells of the eosinophilic series in all stages of maturation. These cells, proven histochemically to be true eosinophils, were abnormal in both maturation and proliferation. Upon electron microscopic study of bone marrow and peripheral blood, abnormalities in the eosinophilic series were identified as early as the promyelocytic stage as well as in the most mature eosinophil seen. The clinical and morphologic picture of this patient's disease raises the possibility of this being an acute eosinophilic leukaemia.