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Haemoglobin F Port Royal (α 2 G γ 2 , 125Glu → Ala )
Author(s) -
Brimhall B.,
Vedvick T. S.,
Jones R. T.,
Ahern E.,
Palomino E.,
Ahern V.
Publication year - 1974
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1974.tb06798.x
Subject(s) - residue (chemistry) , stereochemistry , chemistry , biochemistry
S ummary . A G γ‐chain variant, Hb F Port Royal, with an electrophoretic mobility intermediate between Hb S and Hb C, was found in a Jamaican‐Negro infant, and made up 14–15% of the total Hb F. A glycinamidation procedure was employed to aid in determining the amino‐acid residue substitution of γ 125 Glu → Ala , and the presence of glycinc in position 136.