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Kinetic Evaluation of Haemostasis during Surgery and Wound Healing
Author(s) -
Slichter Sherrill J.,
Funk Donald D.,
Leandoer Lennart E.,
Harker Laurence A.
Publication year - 1974
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1974.tb06779.x
Subject(s) - wound healing , fibrinogen , platelet , hemostasis , surgery , medicine , surgical wound , in vivo , biology , microbiology and biotechnology
S ummary . This study indicates that platelets and fibrinogen are utilized following surgery as a physiological response to tissue injury. The amount and duration of the consumption of haemostatic components is related to the extent of the surgical injury. In vivo counting demonstrates localized accumulation of radioactively tagged platelets and fibrinogen in the surgical wound that proceeds for several days. It is concluded that this consumption reflects the participation of the haemostatic apparatus in wound healing.