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Monitoring Successive Batches of British Comparative Thromboplastin
Author(s) -
Hills M.,
Ingram G. I. C.
Publication year - 1973
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1973.tb01757.x
Subject(s) - thromboplastin , anticoagulant therapy , anticoagulant , medicine , mathematics , statistics , surgery , coagulation
S ummary . Procedures used in the independent monitoring of British Comparative Thromboplastin are described. Recent results from batches of similar thromboplastin have been analysed for differences in their sensitivity to the anticoagulant defect. On the basis of observed variability, the minimum number of tests required to achieve a given level of discrimination between standardized and modified thromboplastins has been calculated to determine the number of readings which should be obtained to give a reasonable certainty of detecting unsatisfactory batches.