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Glucose‐6‐Phosphate Dehydrogenase Deficiency in Maltese Newborn Infants
Author(s) -
Grech J. L.,
Vicatou Maria
Publication year - 1973
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1973.tb01737.x
Subject(s) - glucose 6 phosphate dehydrogenase , glucose 6 phosphate dehydrogenase deficiency , enzyme deficiency , incidence (geometry) , maltese , medicine , dehydrogenase , pediatrics , physiology , endocrinology , enzyme , biology , biochemistry , linguistics , physics , philosophy , optics
S ummary . A survey was carried out to establish the incidence of erythrocyte glucose‐6‐phosphate dehydrogenase deficiency in newborn infants in the Maltese islands. Of the infants born during the period of the survey 28.7% were tested: 1147 samples were obtained from male and 1016 samples from female infants. Some degree of enzyme deficiency was detected in 5.1% of the samples, and 1.0% were completely enzyme deficient; 5.8% of the male infants and 4.1% of the female infants were enzyme deficient, but only 1.5% of the males and 0.4% of the females were completely deficient. The results are compared with those of a previous survey carried out on the child and adult populations of the islands. G‐6‐PD deficiency was not found in association with the foetal haemoglobin variant Hb F(Malta).