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Copper and Zinc Concentration in the Plasma of Leukaemic Children
Author(s) -
Delves H. T.,
Alexander F. W.,
Lay Helen
Publication year - 1973
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1973.tb01678.x
Subject(s) - zinc , copper , plasma concentration , plasma , chemistry , medicine , plasma levels , endocrinology , physics , organic chemistry , quantum mechanics
S ummary . The concentrations of copper and zinc have been measured in the plasma of children with acute lymphoblastic leukaemia before and after treatment, and compared with healthy controls. The plasma copper concentrations were higher and the plasma zinc concentrations lower for the untreated leukaemic children than for the other two groups. The concentrations of both metals were altered after treatment to values approaching the normal range. The plasma copper: zinc ratio discriminated well between the untreated leukaemic children and the other two groups. This ratio might prove useful in monitoring the response to treatment.