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The Inclusions of the May‐Hegglin Anomaly and Dohle Bodies of Infection: an Ultrastructural Comparison
Author(s) -
Cawley J. C.,
Hayhoe F. G. J.
Publication year - 1972
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1972.tb05694.x
Subject(s) - basophilic , ultrastructure , pathology , biology , anomaly (physics) , medicine , physics , condensed matter physics
S ummary Marked differences in the ultrastructures of the inclusion of the May‐Hegglin anomaly and the Dohle bodies of infection are described. Previously these two inclusions have been considered essentially similar, and the inclusions of the May‐Hegglin anomaly have been called‘Döhle bodies’ . It is suggested that in future the term‘Döhle body’ should be restricted to the basophilic inclusions seen in neutrophils in a variety of infectious states. The distribution of the two inclusions in the different haematological cell types is described, and their functional significance is discussed.