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Studies of the Antibody on the Platelet Surface in Patients with Factor‐VIII Inhibitors
Author(s) -
Ali M. A. M.,
Blajchman M. A.
Publication year - 1972
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1972.tb05683.x
Subject(s) - antibody , platelet , haemophilia , medicine , immunology , haemophilia a , surface immunoglobulin , gastroenterology , surgery , b cell
S ummary An IgG $kP immunoglobulin was present on the surface of the platelets in four of five patients with factor‐VIII inhibitor. A similar antibody was found in the plasma of two out of three patients. Serum IgM was subnormal in two out of three patients with‘idiopathic’ acquired factor‐VIII inhibitor, while the two patients with haemophilia A (with inhibitors) had normal serum immunoglobuhns.