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The Mode of Action of Antibodies which Destroy Factor VIII
Author(s) -
Biggs Rosemary,
Austen D. E. G.,
Denson K. W. E.,
Borrett R.,
Rizza C. R.
Publication year - 1972
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1972.tb03468.x
Subject(s) - antibody , factor (programming language) , chemistry , immunology , medicine , computer science , programming language
S ummary . Antibodies which destroy factor VIII may follow second‐order kinetics (Biggs et al , 1972) or a more complex type of reaction may occur. The present communication concerns the complex reactions and evidence is presented which supports the hypothesis that these antibodies may react with factor VIII to form a complex with some factor‐VIII activity.