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Congenital Dyserythropoietic Anaemia, Type III
Author(s) -
Goudsmit R.,
Beckers Do,
Bruijne J. I.,
Engelfriet C. P.,
James J.,
Morselt A. F. W.,
Reynierse E.
Publication year - 1972
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1972.tb03463.x
Subject(s) - lysis , antibody , serology , microbiology and biotechnology , dna , chemistry , immunology , medicine , biology , biochemistry
S ummary . Cytochemical and serological properties of the erythroid cells of a patient with a congenital dyserythropoietic anaemia, type III, are analysed. Especially striking was the great spread in DNA content per normoblast nucleus. The red cells of the patient were much more readily agglutinated by anti‐i sera than normal cells. Absorption of anti‐I and anti‐i antibodies by the patient's red cells was increased, and there was increased lysis by these antibodies.