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Immunological Homogeneity of Membrane Proteins from Hereditary Spherocytic, Hereditary Elliptocytic, and Normal Red Cells
Author(s) -
Gomperts E. D.,
Metz J.,
Zail S. S.
Publication year - 1971
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1111/j.1365-2141.1971.tb07056.x
Subject(s) - hereditary spherocytosis , hereditary diseases , spherocytosis , immunodiffusion , red cell , hemagglutination , microbiology and biotechnology , biology , ouchterlony double immunodiffusion , immunology , medicine , chemistry , antibody , genetics , gene , antiserum , spleen , splenectomy
S ummary . Haemagglutination inhibition and immunodiffusion techniques were applied to the study of red‐cell membrane protein obtained from normal human subjects, patients with hereditary spherocytosis, patients with hereditary elliptocytosis, and also from calves and monkeys. These techniques failed to detect differences between the normal and abnormal human red cells but did show differences between the red cells of the human and the two other mammalian species.